The Methylation Cycle is the backbone of our physiological and biochemical pathways. Its functional status determines our resistance or susceptibility to environmental toxins and microbes (viruses, bacteria, fungus, and parasites), our ability to synthesize and repair DNA, stabilizing levels of homocysteine in the blood which significantly lowers the risk of cardiovascular disease, heart attacks, strokes and Alzheimer's. This is a confusing array of biochemistry, but suffice it to say, a defect at any one point in these interlocking cycles will inevitably affect the remaining pathways, and your overall health will then suffer.
It was not until 1956 that Roger Williams, Ph.D., a pioneer in nutrition often credited with popularizing the term “biochemical individuality,” wrote the book Biochemical Individuality.
Williams believed that people have different requirements for nutrients, and some may need much greater quantities of nutrients than others in order for their unique biochemistry to function properly. He wrote, “Individuality in nutritional needs is the basis for the genetotrophic approach and for the belief that nutrition applied with due concern for individual genetic variations, which may be large, offers the solution to many baffling health problems.”
Methylation Cycle abnormalities explain why you are sick from environmental toxins while the guy next door is just fine, why you are autistic while your fraternal twin brother is not. While we cannot change your DNA, if we know your weak links we can create "nutritional workarounds" - we can supplement alternative pathways or withhold from your diet, molecules that you cannot handle. If we do not address the Methylation Cycle abnormalities that underlie unexplained or chronic illness - well then the illnesses will remain chronic and unexplained, because it is the Methyl Cycle Abnormalities that predisposed you to ill health.